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Cisplatin pdf

: 1963
: 3
: May 06, 2011
: University Of Pittsburgh Medical Center
Total Page(s)
: 2
Cisplatin - page 1
UPMC C UPMC Cancer Centers Information for Patients Other Names: Platinol ® , platinum isplatin (Generic Name) About This Drug Cisplatin is a drug used to treat cancer. This drug is given intravenously (IV). • numbness or tingling in your fingers, toes, or face • blurred vision • soreness of the mouth and throat. You may have red areas, white patches, or sores that are painful. Possible Side Effects • Sexual problems and reproduction concerns • Allergic reactions to this drug are rare, but may occur. In men and women both, this may occur in some patients. Signs of allergic drug may temporarily or permanently affect reaction are rash or itching, dizziness or light- your ability to have children. This cannot be headedness, shortness of breath, or palpita- determined before your therapy. In men, this tions (feeling your heart beat rapidly). drug may interfere with your ability to have • bone marrow depression. This is a decrease sexual relations. In women, menstrual bleed- in the number of white blood cells, red blood ing may become irregular or stop while you cells, and platelets. Bone marrow depression are receiving this drug. Do not assume that usually occurs 18 to 23 days after the drug is you cannot become pregnant if you do not given and may increase your risk of infection, have a menstrual period. Women may experi- fatigue, and bleeding. ence signs of menopause like vaginal dryness • nausea and vomiting. These symptoms may or itching. occur within the first hour of treatment and This drug may have harmful effects on the may last for a few days to a week. unborn child, so effective methods of birth • changes in kidney function. This drug may control should be used during your cancer effect how your kidneys work. You may expe- treatment. rience a decrease in urination, weight gain, or Genetic counseling is available to you to abnormal changes in your electrolytes. You discuss the effect of this drug therapy on may develop anemia, which is a low red blood future pregnancies. In addition, a genetic cell count that may cause you to feel extreme- counselor can review the potential risks ly tired. Your kidney function will be checked of problems in the fetus due to this medi- as needed. cation if an exposure during pregnancy • High-frequency hearing loss may occur. Us- has occurred. ing IV fluids before and during the cisplatin infusion may reduce or prevent this condition. Occasionally ringing in the ears occurs. continued
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Cisplatin - page 2
CISPLATIN continued Treating Side Effects • Ask your doctor or nurse about medica- tion that is available to help you prevent or lessen nausea or vomiting. • Mouth care is very important. Your mouth care should consist of regular, gentle clean- ing of your teeth or dentures and rinsing your mouth with a mixture of 1/2 teaspoon of salt in 8 ounces of water or 1/2 teaspoon of sodium bicarbonate (baking soda) in 8 ounces of water. This should be done at least after every meal and at bedtime. • Avoid mouthwash that contains alcohol. Avoid alcohol and smoking because they can irritate your mouth. • Use effective methods of birth control dur- ing your cancer treatment. • Vaginal lubricants can be used to lessen vag- inal dryness, itching, and pain during sexual relations. • Speak with your doctor or nurse if you plan to have children. Ask for information on sperm or egg banking. • Drink plenty of fluids for 24 hours after receiving this drug. Call your doctor or nurse immediately if you have any of the following symptoms: • rash or itching, dizziness or lightheadedness, palpitations, shortness of breath • wheezing • swelling of face • fever of 100.5 F (38 C) or higher • chills • unusual bleeding or bruising • decrease in urine output • weight gain of five pounds or more in one week • nausea that prevents you from eating or drinking • vomiting more than twice in one day Call your doctor or nurse as soon as possible if you have the following symptoms: • numbness, tingling, or decreased sensation in fingers, toes, or face • clumsiness in buttoning clothes, opening jars, or other routine activities • changes in vision • changes in hearing • painful mouth or throat that makes it difficult to eat or drink • extreme fatigue that interferes with normal activities UPMC Cancer Centers Information for Patients Food and Drug Interactions There are no known interactions of cisplatin with food. This drug may interact with other medications. Tell your doctor and pharmacist all the medications that you are currently taking. When to Call the Doctor UPMC Cancer Centers work in tandem with the University of Pittsburgh Cancer Institute, the region’s only National Cancer Institute-designated Comprehensive Cancer Center. For information about cancer, call the UPMC Cancer Cen- ters Cancer Information and Referral Service at 412-647-2811 or visit our website at Pittsburgh, PA, USA © University of Pittsburgh Medical Center 2006 MC9507 JBS/AL REV 01/03 Form # 3693-82190-0706 The University of Pittsburgh Medical Center is an equal opportunity employer. Policy prohibits discrimination or harassment on the basis of race, color, religion, na- tional origin, ancestry, sex, age, marital status, familial status, sexual orientation, disability, or veteran status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations. This information is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have.
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